Anti-ABI3抗体ABI3 is thought to inhibit tumor metastasis. In vitro, ABI3 reduces cell motility.

产品编号 yb-5985R
英文名称 Anti-ABI3抗体
中文名称 ABI基因家族2抗体
别    名 ABI gene family member 3; Nesh; New molecule including SH3; ABI3_HUMAN.
Anti-ABI3抗体   
说 明 书 0.1ml  0.2ml  
研究领域 肿瘤  免疫学  染色质和核信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Sheep, 
产品应用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ABI3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
ABI3 is thought to inhibit tumor metastasis. In vitro, ABI3 reduces cell motility.

Function:
May inhibit tumor metastasis. In vitro, reduces cell motility.

Subunit:
May interact with PAK1 and PAK2. Probably interacts with TARSH.

Subcellular Location:
Cytoplasm. Note=Colocalizes with PAK2 at leading edge of cells. 

Tissue Specificity:
Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle. 

Similarity:
Belongs to the ABI family. 
Contains 1 SH3 domain.

Gene ID:
25890


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.