Anti-ARL11抗体This gene encodes a tumor suppressor related to the ADP-ribosylation factor （ARF） family of proteins.

产品编号 yb-5987R
英文名称 Anti-ARL11抗体
中文名称 ADP核糖基化因子样11抗体
别    名 ADP ribosylation factor like 11; ADP ribosylation factor like protein 11; ADP ribosylation factor like tumor suppressor protein 1; ADP-ribosylation factor-like protein 11; ADP-ribosylation factor-like tumor suppressor protein 1; ARL11; ARL11_HUMAN; ARLTS1.
Anti-ARL11抗体
说 明 书 0.1ml  
研究领域 肿瘤  细胞生物  免疫学  信号转导  G蛋白偶联受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21 kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARL11
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers. [provided by RefSeq, May 2010]. 

Function:
May play a role in apoptosis. May act as a tumor suppressor. 

Tissue Specificity:
Expressed in lung and leukocytes. 

DISEASE:
Defects in ARL11 may be a cause of susceptibility to chronic lymphocytic leukemia (CLL) [MIM:151400]. 

Similarity:
Belongs to the small GTPase superfamily. Arf family. 

Database links:
UniProtKB/Swiss-Prot: Q969Q4.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.