Anti-Ephrin B3抗体May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro.

产品编号 yb-7043R
英文名称Anti-Ephrin B3抗体
中文名称 *蛋白激酶B3抗体
别    名 Ephrin B3; EphrinB3 antibody EPH related receptor transmembrane ligand ELK L3; EPH related receptor tyrosine kinase ligand 8; Ephrin B3; EphrinB3; EPLG 8; LERK 8; EFL 6; EFL6; EFNB 3; EFNB3; EFNB3_HUMAN; EPH related receptor transmembrane ligand ELKL3; EPH-related receptor transmembrane ligand ELK-L3; EPH-related receptor tyrosine kinase ligand 8; Ephrin-B3; EPLG8; LERK-8; LERK8.
Anti-Ephrin B3抗体  
说 明 书 0.2ml  
研究领域 心血管  细胞生物  神经生物学  信号转导  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Ephrin B3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.
Tissue specificity: Highly expressed in brain; expressed in embryonic floor plate, roof plate and hindbrain segments.

Subunit:
Interacts with GRIP1 and GRIP2. Binds to Nipah virus G protein.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Highly expressed in brain; expressed in embryonic floor plate, roof plate and hindbrain segments.

Similarity:
Belongs to the ephrin family.
Contains 1 ephrin RBD (ephrin receptor-binding) domain.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.