Anti-DRIL1抗体This gene encodes a member of the ARID （AT-rich interaction domain） family of DNA binding proteins.

产品编号 yb-13031R
英文名称 Anti-DRIL1抗体
中文名称 B淋巴细胞转录调节相关蛋白DRIL1抗体
别    名 ARI3A_HUMAN; ARID domain-containing protein 3A; ARID3A; AT rich interactive domain-containing protein 3A; AT-rich interactive domain-containing protein 3A; B cell regulator of IgH transcription; B-cell regulator of IgH transcription; Bright; dead ringer like 1; Dead ringer-like protein 1; DRIL1; DRIL3; E2F binding protein 1; E2F-binding protein 1; E2FBP1.
Anti-DRIL1抗体
说 明 书 0.1ml  0.2ml  
研究领域 肿瘤  转录调节因子  细胞分化  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 63kDa
细胞定位 细胞核 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DRIL1/ARID3A
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]

Function:
Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation.

Subunit:
Homodimer. Heterodimer with ARID3B. Interacts with E2F1. Interacts with GTF2I and BTK. 

Subcellular Location:
Nucleus. Cytoplasm. Shuttles between nucleus and cytoplasm.

Tissue Specificity:
Widely expressed, with highest expression in skeletal muscle, thalamus, and colon.

Similarity:
Contains 1 ARID domain.
Contains 1 REKLES domain.