Anti-ACKAP2抗体Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner.

产品编号 yb-7745R
英文名称 Anti-ACKAP2抗体
中文名称 细胞骨架相关蛋白2/肿瘤和微管相关蛋白抗体
别    名 Tumor and microtubule associated protein; LB1; se20 10; Tumor associated microtubule associated protein; AI461656; CKAP 2; Ckap2; CKAP2_HUMAN; CTCL tumor antigen se20 10; CTCL tumor antigen se20-10; Cytoskeleton associated protein 2; Cytoskeleton-associated protein 2; DKFZp686L1238; TMAP; Tumor- and microtubule-associated protein.
Anti-ACKAP2抗体   
说 明 书 0.2ml  
研究领域 肿瘤  细胞生物  信号转导  细胞周期蛋白  细胞分化  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Horse, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 77kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CKAP2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner.
Tissue specificity: Abundant in testis, thymus, and in tumor derived cell lines, while barely detectable in liver, prostate, and kidney.

Subunit:
Associates with alpha- and beta-tubulins

Subcellular Location:
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. 

Tissue Specificity:
Abundant in testis, thymus, and in tumor derived cell lines, while barely detectable in liver, prostate, and kidney.

Similarity:
Belongs to the CKAP2 family.

Database links:
UniProtKB/Swiss-Prot: Q8WWK9.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.