Anti-FAAH2抗体This gene encodes a fatty acid amide hydrolase that shares a conserved protein motif with the amidase signature family

产品编号 yb-5119R
英文名称 Anti-FAAH2抗体
中文名称 脂肪酸酰胺水解酶2抗体
别    名 AMDD; amidase domain containing; Amidase domain-containing protein; Anandamide amidohydrolase 2; FAAH-2; FAAH2; FLJ31204; Oleamide hydrolase 2; RP11-479E16; RP11-479E16.1; FAAH2_HUMAN.
Anti-FAAH2抗体   
说 明 书 0.1ml  0.2ml  
研究领域 肿瘤  细胞生物  免疫学  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human FAAH2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
This gene encodes a fatty acid amide hydrolase that shares a conserved protein motif with the amidase signature family of enzymes. The encoded enzyme is able to catalyze the hydrolysis of a broad range of bioactive lipids, including those from the three main classes of fatty acid amides; N-acylethanolamines, fatty acid primary amides and N-acyl amino acids. This enzyme has a preference for monounsaturated acyl chains as a substrate.[provided by RefSeq, Sep 2009]

Function:
Degrades bioactive fatty acid amides like oleamide, theendogenous cannabinoid, anandamide and myristic amide to theircorresponding acids, thereby serving to terminate the signalingfunctions of these molecules. Hydrolyzes monounsaturated substrateanandamide preferentially as compared to polyunsaturatedsubstrates.

Subunit:
Homodimer

Subcellular Location:
Membrane; Single-pass membrane protein

Tissue Specificity:
Highly expressed in the brain, small intestineand testis. Also expressed in the heart, kidney, liver, lung andprostate.

Similarity:
Belongs to the amidase family.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.