Anti-ETAA1/ETAA16抗体ETAA16 （Ewing's tumor-associated antigen 16）, also known as ETAA1, is a 926 amino acid cytoplasmic protein that

产品编号 yb-14640R
英文名称Anti-ETAA1/ETAA16抗体
中文名称 尤文氏瘤相关抗原1抗体
别    名 Etaa1; ETAA1_HUMAN; Ewing''s tumor-associated antigen 1; Ewing''s tumor-associated antigen 16; ETAA16.
Anti-ETAA1/ETAA16抗体
说 明 书 0.2ml  
研究领域 肿瘤  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 103kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ETAA1/ETAA16
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.

PubMed PubMed
产品介绍 background:
ETAA16 (Ewing's tumor-associated antigen 16), also known as ETAA1, is a 926 amino acid cytoplasmic protein that is highly expressed in kidney, brain, liver and Ewing tumor cell lines. ETAA16 undergoes post-translational phosphorylation following DNA damage, most likely by either ATM or ATR, and is suggested to function as a tumour-specific cell surface antigen in Ewing's family of tumour cell lines. The gene encoding ETAA16 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximay 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.