Anti-ELOVL7抗体Elongation of very long chain fatty acid-like （ELOVL） proteins are members of the ELO family of proteins,

产品编号 yb-14573R
英文名称Anti-ELOVL7抗体
中文名称 ELOVL7蛋白抗体
别    名 3-keto acyl-CoA synthase Elovl7; Elongation of very long chain fatty acids protein 7; ELOV7_HUMAN; ELOVL family member 7 elongation of long chain fatty acids; ELOVL family member 7 elongation of long chain fatty acids yeast; ELOVL fatty acid elongase 7; ELOVL7.
Anti-ELOVL7抗体  
说 明 书 0.2ml  
研究领域 细胞生物  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ELOVL7
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.

PubMed PubMed
产品介绍 background:
Elongation of very long chain fatty acid-like (ELOVL) proteins are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. Fatty acids are important in many biological processes including fetal growth and development, brain development, inflammatory response, and retinal function. The ELOVL proteins function as elongases and catalyze fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids protein 7 (ELOVL7) is involved in lipogenesis and its expression is regulated by PPAR? ELOVL7 is a 281 amino acid protein and the gene encoding ELOVL7 maps to chromosome 5q12.1.

Function:
Condensing enzyme that catalyzes the synthesis of saturated and polyunsaturated very long chain fatty acids. Highest activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Expressed in most tissues except heart and skeletal muscle.

Similarity:
Belongs to the ELO family.