Anti-EI2BL抗体Catalyzes the interconversion of methylthioribose-1-phosphate （MTR-1-P） into methylthioribulose-1-phosphate （MTRu-1-P）.

产品编号 yb-14530R
英文名称 Anti-EI2BL抗体
中文名称 EI2BL蛋白抗体
别    名 EI2BL; M1Pi; Mediator of RhoA-dependent invasion; Methylthioribose 1 phosphate isomerase 1; Methylthioribose 1 phosphate isomerase homolog; Methylthioribose-1-phosphate isomerase; MGC3207; MRDI; mri1; MTNA; MTNA_HUMAN; MTR-1-P isomerase; S methyl 5 thioribose 1 phosphate isomerase 1; S-methyl-5-thioribose-1-phosphate isomerase; Translation initiation factor eIF 2B; Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein; Ypr118w.
 Anti-EI2BL抗体
说 明 书 0.2ml  
研究领域 细胞生物  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
细胞定位 细胞核 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human EI2BL
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
 
PubMed PubMed
产品介绍 Function:
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.

Subcellular Location:
Nucleus. Cytoplasm. Cell projection. Primarily nuclear, but cytoplasmic in cancer cells, with enrichment at leading edge of the plasma membrane in late stage tumor cells.
 
Similarity:
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.