Anti-EFCAB1抗体Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions

产品编号 yb-14507R
英文名称Anti-EFCAB1抗体
中文名称 EFCAB1蛋白抗体
别    名 EF-CAB1; EF-hand calcium binding domain 1; EF-hand calcium-binding domain-containing protein 1; EFCAB1; EFCB1_HUMAN.
Anti-EFCAB1抗体    
说 明 书 0.2ml  
研究领域 细胞生物  信号转导  转运蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Rabbit, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human EFCAB1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The gene encoding EF-CAB1 (EF-hand calcium-binding domain-containing peptide protein 1) is located on the long arm of chromsome 8. This 211 amino acid protein contains 3 EF-hand domains, which are helix-loop-helix structures that are usually found in calcium binding proteins. Other well-studied calcium binding proteins that contain EF-hand motifs include calmodulin (CaM), Troponin C, myosin regulatory light chain (MYL) and S-100 proteins.

Similarity:
Contains 3 EF-hand domains.