Anti-EBNA 3B抗体EBNA 3B is one of only 10 viral proteins expressed in Epstein Barr Virus （EBV） transformed B lymphoblasts cultured

产品编号 yb-4698R
英文名称 Anti-EBNA 3B抗体
中文名称 EB病毒核抗原-3B抗体
别    名 EBNA 4; EBV; EBV nuclear antigen 4; Epstein Barr nuclear antigen 4; HHV4; EBNA4_EBVB9; Epstein-Barr nuclear antigen 4; EBNA-4; EBV nuclear antigen 4; Epstein-Barr nuclear antigen 3B; EBNA-3B; EBV nuclear antigen 3B.
Anti-EBNA 3B抗体
说 明 书 0.2ml  
研究领域 肿瘤  细胞生物  免疫学  细菌及病毒  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Epstein Barr Virus
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 103kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from Epstein Barr Virus EBNA 3B
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
EBNA 3B is one of only 10 viral proteins expressed in Epstein Barr Virus (EBV) transformed B lymphoblasts cultured in vitro, though the expression of EBNA 3B is not required for EBV-mediated transformation in vitro. This 165kDa nuclear protein functions as a transcription factor.

Function:
May be involved in transcriptional regulation of both viral and cellular genes by interacting with the host DNA-binding protein RBPJ.

Subunit:
Interacts (via N-terminus) with host RBPJ.

Subcellular Location:
Host nucleus. 

Similarity:
Belongs to the herpesviridae EBNA-4 family.