Anti-DZIP1L抗体Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions,

产品编号 yb-14479R
英文名称 Anti-DZIP1L抗体
中文名称 DZIP1L蛋白抗体
别    名 DAZ-interacting protein 1-like protein; DZI1L_HUMAN; Dzip1l; DZIP2; Zinc finger protein DZIP1L.
Anti-DZIP1L抗体   
说 明 书 0.2ml  
研究领域 细胞生物  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Horse, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 87kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DZIP1L
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. DZIP1L (DAZ interacting protein 1-like), also known as DZIP2, is a 767 amino acid protein that contains one C2H2-type zinc finger and may play a role in transcriptional regulation. Multiple isoforms of DZIP1L exist due to alternative splicing events. The gene encoding DZIP1L maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Similarity:
Belongs to the DZIP C2H2-type zinc-finger protein family.
Contains 1 C2H2-type zinc finger.