Anti-Dystrophin抗体Dystoin （DYTN） is a 578 amino acid cell membrane protein that contains one ZZ-type zinc finger.

产品编号 yb-14477R
英文名称 Anti-Dystrophin抗体
中文名称 抗肌萎缩蛋白抗体
别    名 DMD_HUMAN; Dystrophin.
 Anti-Dystrophin抗体 
说 明 书 0.2ml  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Sheep, 
产品应用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 426kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Dystrophin
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for  
PubMed PubMed
产品介绍 background:
Dystoin (DYTN) is a 578 amino acid cell membrane protein that contains one ZZ-type zinc finger. The gene that encodes dystroin maps to human chromosome 2, which makes up approximay 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial omeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.

Subcellular Location:
Cell membrane.

Similarity:
Contains 1 ZZ-type zinc finger.

 
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.