Anti-DYRK4抗体This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases.

产品编号yb-14474R
英文名称 Anti-DYRK4抗体
中文名称 双特异性*磷酸化调节激酶4抗体
别    名 Dual specificity tyrosine phosphorylation regulated kinase 4; Dual specificity tyrosine-phosphorylation-regulated kinase 4; Dyrk4; DYRK4_HUMAN; EC 2.7.12.1.
Anti-DYRK4抗体   
说 明 书 0.2ml  
研究领域 细胞生物  信号转导  细胞分化  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DYRK4
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Aug 2013]

Function:
Possible non-essential role in spermiogenesis.

Subcellular Location:
Cytoplasm.

Post-translational modifications:
Autophosphorylated on tyrosine residues.

Similarity:
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
Contains 1 protein kinase domain.