Anti-DUSP28抗体Dual specificity phosphatases （DSPs） are a subclass of the protein tyrosine phosphatase （PTP） gene superfamily,

产品编号 yb-14460R
英文名称 Anti-DUSP28抗体
中文名称 双特异性磷酸酶抗体28抗体
别    名 Dual specificity phosphatase 28; DUSP28; DUS28_HUMAN; VHP.
Anti-DUSP28抗体  
说 明 书 0.2ml  
研究领域 细胞生物  信号转导  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 18kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DUSP28
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.

PubMed PubMed
产品介绍 background:
Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members. DUSP28 is a 176 amino acid protein that belongs to the protein-tyrosine phosphatase family and non-receptor class dual specificity subfamily. Containing one tyrosine-protein phosphatase domain, DUSP28 is encoded by a gene that maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximay 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2, including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome.

Function:
DUSP28 belongs to the protein-tyrosine phosphatase family, non-receptor class dual specificity subfamily. It contains one tyrosine-protein phosphatase domain.

Similarity:
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 tyrosine-protein phosphatase domain. 


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.