Anti-DUSP23抗体Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues.

产品编号 yb-14456R
英文名称 Anti-DUSP23抗体
中文名称 双特异性磷酸酶抗体23抗体
别    名 Dual specificity phosphatase 23; Dual specificity protein phosphatase 23; DUS23_HUMAN; Dusp23; DUSP25; EC 3.1.3.16; EC 3.1.3.48; FLJ20442; LDP 3; LDP-3; LDP3; Low molecular mass dual specificity phosphatase 3; MOSP; RP11-190A12.1; VH1 like member Z; VH1 like phosphatase Z; VH1-like phosphatase Z; VHZ.
Anti-DUSP23抗体
说 明 书 0.2ml  
研究领域 细胞生物  信号转导  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DUSP23
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14).

Subcellular Location:
Cytoplasm; cytosol. Nucleus. Mainly cytosolic. Also nuclear.

Tissue Specificity:
Widely expressed. Highly expressed in spleen, prostate, colon, adrenal gland, mammary gland, thyroid and trachea. Expressed at lower level in uterus, small intestine, bladder, bone marrow, brain, spinal cord and stomach.

Similarity:
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 tyrosine-protein phosphatase domain.