Anti-DUB3抗体DUB3 is a member of the ubiquitin processing protease （UBP） subfamily of deubiquitinating enzymes.

产品编号yb-14440R
英文名称 Anti-DUB3抗体
中文名称 去泛素蛋白3抗体
别    名 Cytokine inducible Deubiquitinating Enzyme; Deubiquitinating enzyme 17-like protein 2; Deubiquitinating enzyme 3; Deubiquitinating protein 3; DUB-3; DUB3 protein; U17L2_HUMAN; Ubiquitin carboxyl-terminal hydrolase 17-like protein 2; Ubiquitin thiolesterase 17-like protein 2; Ubiquitin-specific-processing protease 17-like protein 2; USP17L2.
Anti-DUB3抗体  
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  细胞凋亡  细胞周期蛋白  表观遗传学  泛素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DUB3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
DUB3 is a member of the ubiquitin processing protease (UBP) subfamily of deubiquitinating enzymes. See USP1 (MIM 603478) for background information.[supplied by OMIM, Mar 2008]

Function:
Deubiquitinating enzyme that specifically removes conjugated ubiquitin from CDC25A, thereby playing a key role in cell cycle regulation. Deubiquitination of CDC25A prevents its degradation by the proteasome during the G1/S and G2/M phases of the cell cycle and is required for cell-cycle progression. Has transforming capabilities on cell lines. May also function in cell apoptosis.