Anti-DPEP1抗体The protein encoded by this gene is a kidney membrane enzyme involved in the metabolism of glutathione

产品编号 yb-14414R
英文名称 Anti-DPEP1抗体
中文名称 脱氢肽酶1抗体
别    名 Dehydropeptidase-I; Dipeptidase 1 (renal); Dipeptidase 1; DPEP1; DPEP1_HUMAN; hRDP; MBD1; MDP; Microsomal dipeptidase; RDP; Renal dipeptidase.
Anti-DPEP1抗体  
说 明 书 0.1ml  0.2ml  
研究领域 肿瘤  心血管  细胞生物  神经生物学  泛素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 44kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DPEP1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
The protein encoded by this gene is a kidney membrane enzyme involved in the metabolism of glutathione and other similar proteins by dipeptide hydrolysis. The encoded protein is known to regulate leukotriene activity by catalyzing the conversion of leukotriene D4 to leukotriene E4. This protein uses zinc as a cofactor and acts as a disulfide-linked homodimer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2012]

Function:
Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity.

Subcellular Location:
Apical cell membrane. Cell projection; microvillus membrane. Brush border membrane.

Similarity:
Belongs to the peptidase M19 family.