Anti-DOPEY1抗体Dopey-1 is a 2,465 amino acid protein that is thought to be involved in protein trafficking between the

产品编号 yb-14409R
英文名称 Anti-DOPEY1抗体
中文名称 迟钝蛋白家族1抗体
别    名 Dopey-1; DOP1; DOP1_HUMAN; Dopey family member 1; DOPEY1; KIAA1117; Protein dopey 1; Protein dopey-1.
Anti-DOPEY1抗体   
说 明 书 0.1ml  0.2ml  
研究领域 神经生物学  信号转导  转运蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
产品应用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 277kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DOPEY1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Dopey-1 is a 2,465 amino acid protein that is thought to be involved in protein trafficking between the late golgi and early endosomes and may be involved in neurological alternations and mental retardation associated with Down syndrome. The gene encoding Dopey-1 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

Function:
May be involved in protein traffic between late Golgi and early endosomes.

Similarity:
Belongs to the dopey family