Anti-DHRS7抗体DHRS7 （dehydrogenase/reductase （SDR family） member 7）, also known as SDR34C1, CGI-86 or retSDR4,

产品编号yb-8262R
英文名称 Anti-DHRS7抗体
中文名称 视网膜短链脱氢酶/还原酶家族7抗体
别    名 CGI 86; CGI86; Dehydrogenase/reductase SDR family member 7; DHRS7A; retDSR4; Retinal short chain dehydrogenase/reductase 4; RETSDR4; DHRS7_HUMAN.
Anti-DHRS7抗体
说 明 书 0.2ml  
研究领域 细胞生物  免疫学  发育生物学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Rabbit, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DHRS7
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.

PubMed PubMed
产品介绍 background:
DHRS7 (dehydrogenase/reductase (SDR family) member 7), also known as SDR34C1, CGI-86 or retSDR4, is a 339 amino acid member of the SDR family. Like other members of the SDR family, DHRS7 contains a cofactor-binding Rossman-fold domain and is thought to catalyze the oxidation and reduction of a variety of substrates such as steroids and retinoids. DHRS7 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 

Database links:
UniProtKB/Swiss-Prot: Q9Y394.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.