Anti-DDRGK1抗体DDRGK1 （DDRGK domain-containing protein 1）, also known as C20orf116, is a 314 amino acid secreted protein.

产品编号 yb-8252R
英文名称 Anti-DDRGK1抗体
中文名称 DDRGK1蛋白抗体
别    名 Chromosome 20 open reading frame 116; DDRGK domain containing 1; DDRGK domain containing protein 1; DDRGK domain-containing protein 1; DDRGK_HUMAN; Ddrgk1; MGC2592; RGD1309979; RP23-100C5.9; dJ1187M17.3; 1110001I20Rik; 2600009E05Rik; C20orf116.
Anti-DDRGK1抗体 
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  免疫学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DDRGK1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
DDRGK1 (DDRGK domain-containing protein 1), also known as C20orf116, is a 314 amino acid secreted protein. DDRGK1 contains one PCI domain and is expressed as two isoforms produced by alternative splicing. The gene that encodes DDRGK1 maps to human chromosome 20, which represents about 2% of human DNA and consists of approximay 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis, which are thought to be important for seminal production. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20. 

Subcellular Location:
Endoplasmic reticulum. 

Tissue Specificity:
Ubiquitously expressed (at protein level).

Post-translational modifications:
Ufmylated. Conjugated to ubiquitin-like protein UFM1, probably at Lys-267. The role of ufmylation is unclear.