Anti-COX7B2抗体The cytochrome c oxidase （COX） family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane,

产品编号 yb-14015R
英文名称Anti-COX7B2抗体
中文名称 *氧化酶蛋白7B2抗体
别    名 COX7B2; CX7B2_HUMAN; Cytochrome c oxidase polypeptide VIIb2; Cytochrome c oxidase subunit 7B2 mitochondrial; Cytochrome c oxidase subunit 7B2, mitochondrial; Cytochrome c oxidase subunit VIIb2; MGC102754.
Anti-COX7B2抗体
说 明 书 0.1ml  0.2ml  
研究领域 肿瘤  细胞生物  信号转导  新陈代谢  线粒体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 6.2kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human COX7B2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimay resulting in the production of water and ATP. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX7b (cytochrome c oxidase subunit VIIb polypeptide) and COX7b2 (cytochrome c oxidase subunit VIIb polypeptide 2) are 80 and 81 amino acid proteins, respectively, which exist as components of the COX complex, therefore playing an important role in electron transport. A rare polymorphism in the COX7b2 gene at codon 26 may be linked to nasopharyngeal carcinoma (NPC), the most common head and neck cancer in southern China.

Function:
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Subcellular Location:
Mitochondrion inner membrane.

Similarity:
Belongs to the cytochrome c oxidase VIIb family.