Anti-CORO2A抗体This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximay 40

产品编号 yb-13996R
英文名称 Anti-CORO2A抗体
中文名称 肌动蛋白结合蛋白2A抗体
别    名 CLIPINB; COR2A_HUMAN; CORO 2A; CORO2A; Coronin 2A; Coronin actin binding protein 2A; Coronin like protein B; Coronin-2A; DKFZp686G19226; IR10; OTTHUMP00000021767; OTTHUMP00000021768; WD protein IR10; WD repeat containing protein 2; WD repeat protein 2; WD repeat-containing protein 2; WDR2.
规格价格 0.1ml/800元 购买    0.2ml/1280元 购买    
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CORO2A
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-CORO2A抗体
PubMed PubMed
产品介绍 background:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximay 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]

Subunit:
Binds actin (By similarity). Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1R, CORO2A and GPS2.

Similarity:
Belongs to the WD repeat coronin family.
Contains 5 WD repeats.