Anti-C21orf66抗体C21orf66, also known as GCFC （GC-rich sequence DNA-binding factor）, is a 917 amino acid protein that localizes to

产品编号 yb-13758R
英文名称 Anti-C21orf66抗体
中文名称 21号染色体开放阅读框66抗体
别    名 BM 020; BM020; Chromosome 21 open reading frame 66; FSAP105; Functional spliceosome-associated protein 105; GC rich sequence DNA binding factor candidate; GC-rich sequence DNA-binding factor 1; GCFC; GCFC1; PAXB1_HUMAN; PAX3 and PAX7 binding protein 1; PAXBP1.
Anti-C21orf66抗体
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  神经生物学  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 105kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human C21orf66
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
C21orf66, also known as GCFC (GC-rich sequence DNA-binding factor), is a 917 amino acid protein that localizes to the nucleus and belongs to the GCF family. Expressed ubiquitously, C21orf66 functions as a possible transcription factor and exists as four alternatively spliced isoforms, designated A, B, C and D. The gene encoding C21orf66 maps to human chromosome 21, which houses approximay 300 genes and comprises nearly 1.5% of the human genome. Chromosome 21-associated disorders include Alzheimer's Disease, amyotrophic lateral sclerosis and, most notably, Down Syndrome (also known as trisomy 21.

Function:
Possible transcription factor.