Anti-C7orf53抗体Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly,

产品编号 yb-15273R
英文名称Anti-C7orf53抗体
中文名称 7号染色体开放阅读框53抗体
别    名 C7orf53; CG053_HUMAN; Chromosome 7 open reading frame 53; Coiled-coil domain-containing transmembrane protein C7orf53.
Anti-C7orf53抗体  
说 明 书 0.2ml  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human C7orf53
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. The C7orf53 gene product has been provisionally designated C7orf53 pending further characterization.

Subcellular Location:
Membrane; Single-pass membrane protein (Potential). 

Database links:
UniProtKB/Swiss-Prot: Q8N8F7.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.