Anti-CC21ORF13抗体Leber congenital amaurosis （LCA） is one of the most common causes of hereditary blindness or severe visual impairment in infants.

产品编号 yb-15123R
英文名称 Anti-CC21ORF13抗体
中文名称 21号染色体开放阅读框13抗体
别    名 C21orf13; Chromosome 21 open reading frame 13; Lca5l; LCA5L_HUMAN; Leber congenital amaurosis 5 like; Leber congenital amaurosis 5 like protein; Leber congenital amaurosis 5-like protein; Lebercilin-like protein; MGC33295; OTTHUMP00000069084; OTTHUMP00000069085.
Anti-CC21ORF13抗体
说 明 书 0.2ml  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Horse, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 77kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human C21ORF13
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Leber congenital amaurosis (LCA) is one of the most common causes of hereditary blindness or severe visual impairment in infants. Mutations in several genes with diverse functions mapping to two loci have been implicated in LCA causation. These proteins are involved in processes such as photoreceptor development and maintenance, phototransduction, vitamin A metabolism and protein trafficking. LCA5, also known as Lebercilin, is a ciliary protein that is widely expressed during development and localizes to the connecting cilia of photoreceptors and to the microtubules, centrioles and primary cilia of cultured mammalian cells. The Leber congenital amaurosis 5-like protein (LCA5L) is a 670 amino acid protein that belongs to the LCA5 family. 

Similarity:
Belongs to the LCA5 family.


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.