Anti-C1QTNF8抗体Members of the CTRP （complement C1q tumor necrosis factor-related protein） family are structurally related, although functionally diverse.

产品编号 yb-15084R
英文名称 Anti-C1QTNF8抗体
中文名称 补体C1qTNF8链多肽抗体
别    名 C1q and tumor necrosis factor related protein 8; C1q/TNF-related protein 8; C1QT8_HUMAN; C1QTNF8; Complement C1q tumor necrosis factor-related protein 8; CTRP8; UNQ5829; UNQ5829/PRO19648.
Anti-C1QTNF8抗体 
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human C1QTNF8
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.

PubMed PubMed
产品介绍 background:
Members of the CTRP (complement C1q tumor necrosis factor-related protein) family are structurally related, although functionally diverse. CTRPs share TNF 鍠like globular domains and N-terminal glycine-X-Y repeats and also tend to form trimers that have the ability to congregate into higher order structures. Functions of this protein family range from immune homeostasis to structural and extracelluar matrix-related roles. CTRP8 (complement C1q tumor necrosis factor-related protein 8), also known as UNQ5829 or C1QTNF8 (C1q and tumor necrosis factor related protein 8), is a 252 amino acid secreted protein that is expressed predominantly in lung and testis. Containing one C1q domain and one collagen-like domain, CTRP8 exists as a homotrimer and forms heteromeric complexes with C1qL1. CTRP8 is encoded by a gene located on human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome.

Subunit:
Homotrimer. Forms heteromeric complexes with C1QL1. 

Subcellular Location:
Secreted. 

Tissue Specificity:
Expressed predominantly in lung and testis. 

Post-translational modifications:
No N-glycosylation. 


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.