Anti-CSPS/MPST抗体Cysteine string proteins （CSPs） are synaptic vesicle-associated, secretory vesicle proteins that are involved in Ca2+-regulated exocytosis of synaptic

产品编号 yb-12945R
英文名称 Anti-CSPS/MPST抗体
中文名称 磺基转移酶CSPS抗体
别    名 Aryl sulfotransferase 1A3/1A4; Aryl sulfotransferase; Catecholamine Sulfating Phenol Sulfotransferase; Catecholamine-sulfating phenol sulfotransferase; Dopamine specific sulfotransferase; FLJ54864; HAST; HAST3; M PST; M-PST; Monoamine preferring sulfotransferase; Monoamine sulfating phenosulfotransferase; monoamine-preferring; Monoamine-sulfating phenol sulfotransferase; MPST; Phenol sulfotransferase 1A5; Placental estrogen sulfotransferase; ST1A3/ST1A4; ST1A3_HUMAN; ST1A5; STM; Sulfokinase; Sulfotransferase 1A3/1A4; Sulfotransferase; Sulfotransferase family cytosolic 1A phenol preferring member 3; Sulfotransferase family cytosolic 1A phenol preferring member 4; Sulfotransferase monoamine preferring; SULT1A 3; SULT1A4; Thermolabile (monoamine M form) phenol sulfotransferase; Thermolabile phenol sulfotransferase; TL PST; TL-PST; TLPST.
Anti-CSPS/MPST抗体 
说 明 书 0.1ml  0.2ml  
研究领域 肿瘤  细胞生物  神经生物学  信号转导  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Rabbit, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CSPS
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4
PubMed PubMed
产品介绍 background:
Cysteine string proteins (CSPs) are synaptic vesicle-associated, secretory vesicle proteins that are involved in Ca2+-regulated exocytosis of synaptic vesicles and modulation of presynaptic transmembrane calcium fluxes in neuroendocrine and endocrine cell types. CSP contains a J-domain that binds HSP 70/HSC 70 chaperone ATPases and a membrane-targeting, palmitoylated cysteine-rich string region. CSPs may act as molecular chaperones in synapses, and mediate conformational folding of components of the vesicular exocytotic machinery. CSP is involved in the fine tuning of neurotransmission through its interaction with receptor-coupled trimeric GTP binding proteins (G proteins) and N-type Ca2+ channels. Two variants of CSP have been described: CSP1; and the 31 amino acid, C-terminally truncated isoform, CSP2. Subcellular fractionation of insulinoma cells shows CSP1 in granular fractions, while the membrane and cytosol fractions contain predominantly CSP2. The fractions also contain additional proteins, presumably CSP dimers. Furthermore, in various mammalian cell lines (including rat brain) CSP1 expression predominates CSP2 expression.