Anti-CSGLCAT抗体CSGlcA-T is a 772 amino acid single-pass type II membrane protein of the golgi apparatus that belongs to the chondroitin N-acetylgalactosaminyltransferase family. Widely e产品介绍 background

产品编号 yb-12939R
英文名称 Anti-CSGLCAT抗体
中文名称 *聚合酶3抗体
别    名 Chondroitin sulfate glucuronyltransferase; Chondroitin synthase 3; CSGlcA-T; ChSy 3; ChSy-3; CHPF2; ChPF-2; CSGLCA T; N acetylgalactosaminyl proteoglycan 3 beta glucuronosyltransferase; CHPF2_HUMAN; Chondroitin polymerizing factor 2; Chondroitin sulfate glucuronyltransferase; N acetylgalactosaminyl proteoglycan 3 beta glucuronosyltransferase; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase.
 Anti-CSGLCAT抗体
说 明 书 0.2ml  
研究领域 细胞生物  糖蛋白  细胞类型标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 86kDa
细胞定位 细胞浆 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CSGLCAT
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
 
PubMed PubMed
CSGlcA-T is a 772 amino acid single-pass type II membrane protein of the golgi apparatus that belongs to the chondroitin N-acetylgalactosaminyltransferase family. Widely e产品介绍 background:

xpressed and existing as two alternatively spliced isoforms, CSGlcA-T is found at highest levels in small intestine, pancreas and placenta, with lower levels in heart, brain, kidney, and skeletal muscle where it transfers glucuronic acid from UDP-glucuronic acid to N-acetylgalactosamine residues of elongating chondroitin polymers. The gene encoding CSGlcA-T maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome and Lissencephaly.

Function:
Transfers glucuronic acid (GlcUA) from UDP-GlcUA to N-acetylgalactosamine residues on the non-reducing end of the elongating chondroitin polymer. Has no N-acetylgalactosaminyltransferase activity.

Subcellular Location:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein (Probable).

Tissue Specificity:
Ubiquitous. Highly expressed in placenta, small intestine and pancreas.
 
Similarity:
Belongs to the chondroitin N-acetylgalactosaminyltransferase family