Anti-C11orf21抗体C11orf21 is a 132 amino acid cytoplasmic protein that is expressed exclusively in heart and is encoded by a gene located on human chromosome 11.

产品编号 yb-9936R
英文名称 Anti-C11orf21抗体
中文名称 11号染色体开放阅读框21抗体
别    名 chromosome 11 open reading frame 21; CK021_HUMAN; Uncharacterized protein C11orf21.
Anti-C11orf21抗体
说 明 书 0.2ml  
研究领域 心血管  细胞生物  免疫学  神经生物学  细胞周期蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human C11orf21
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
C11orf21 is a 132 amino acid cytoplasmic protein that is expressed exclusively in heart and is encoded by a gene located on human chromosome 11. With approximay 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-angiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed exclusively in heart.

Database links:
UniProtKB/Swiss-Prot: Q9P2W6.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.