Anti-C2ORF25抗体C2ORF25 is a mitochondrial protein and its function is not fully identified. But, Vitamin B12 （cobalamin） is an essential

产品编号 yb-9808R
英文名称 Anti-C2ORF25抗体
中文名称 2号染色体开放阅读框25抗体
别    名 cblD; Chromosome 2 open reading frame 25; Protein C2orf25, mitochondrial; CL25022; Methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria; Protein C2orf25, mitochondrial; MMAD_HUMAN.
Anti-C2ORF25抗体   
说 明 书 0.2ml  
研究领域 细胞生物  免疫学  线粒体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 IEM=1:20-200 IGS=1:20-200 GICA=1:20-200 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human C2ORF25
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
C2ORF25 is a mitochondrial protein and its function is not fully identified. But, Vitamin B12 (cobalamin) is an essential cofactor in several metabolic pathways. Intracellular conversion of cobalamin to adenosylcobalamin in mitochondria and to methylcobalamin in cytoplasm is necessary for homeostasis of methylmalonic acid and homocysteine. C2ORF25 encodes a protein involved in an early step of cobalamin metabolism.

Function:
nvolved in cobalamin metabolism.

Subcellular Location:
Mitochondrial.