Anti-CCDC88B抗体HkRP3, also known as CCDC88B （coiled-coil domain-containing protein 88B） or BRLZ （brain leucine zipper domain-containing protein）,

产品编号 yb-8141R
英文名称 Anti-CCDC88B抗体
中文名称 大脑*拉链结构域蛋白抗体
别    名 Brain leucine zipper domain containing protein; Brain leucine zipper domain-containing protein; Brain leucine zipper protein; BRLZ; CC88B_HUMAN; CCDC 88; CCDC 88B; Ccdc88b; Coiled coil domain containing 88; Coiled coil domain containing protein 88B; Coiled-coil domain-containing protein 88B; DKFZp434G0920; FLJ00354; FLJ37970; HkRP 3; HkRP3; Hook related protein 3; Hook-related protein 3.
Anti-CCDC88B抗体
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  免疫学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 79kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from Hu CCDC88B/BRLZ/HkRP3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
HkRP3, also known as CCDC88B (coiled-coil domain-containing protein 88B) or BRLZ (brain leucine zipper domain-containing protein), is a 1,476 amino acid protein that belongs to the CCDC88 family. Members of the hook-related protein family are characterized by the presence of a C-terminal hook-related domain and an N-terminal potential microtubule binding domain. HkRP3 may be involved in the linkage of various organelles to microtubules, and exists as six alternatively spliced isoforms. The gene encoding HkRP3 maps to human chromosome 11q13.1 and mouse chromosome 19 A. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Similarity:
Belongs to the CCDC88 family. 

Database links:
UniProtKB/Swiss-Prot: A6NC98.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.