Anti-CLLD7抗体This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB （broad complex, tramtrack and bric-a-brac） domain. In rat,

产品编号 yb-8015R
英文名称 Anti-CLLD7抗体
中文名称 *核苷酸交换因子CLLD7抗体
别    名 RCC1 and BTB domain-containing protein 1; Chronic lymphocytic leukemia deletion region gene 7 protein; CLL deletion region gene 7 protein; Regulator of chromosome condensation and BTB domain-containing protein 1; RCBT1_HUMAN.
Anti-CLLD7抗体  
说 明 书 0.2ml  
研究领域 肿瘤  细胞生物  免疫学  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58-60kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CLLD7
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq, Jul 2008]. 

Function:
May be involved in cell cycle regulation by chromatin remodeling. 

Subcellular Location:
Nucleus (Potential). 

Tissue Specificity:
Ubiquitously expressed. 

Similarity:
Contains 2 BTB (POZ) domains.
Contains 6 RCC1 repeats. 

Database links:
UniProtKB/Swiss-Prot: Q8NDN9.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.