Anti-CEACAM21抗体Carcinoembryonic antigen （CEA） is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEACAM

产品编号 yb-7996R
英文名称 Anti-CEACAM21抗体
中文名称 癌胚抗原相关细胞粘附分子21抗体
别    名 Carcinoembryonic antigen related cell adhesion molecule 21; Carcinoembryonic antigen-related cell adhesion molecule 21; CEA21_HUMAN; CEACAM21; CEACAM3; FLJ13540; MGC119874; OTTHUMP00000199036; R29124_1.
Anti-CEACAM21抗体 
说 明 书 0.2ml  
研究领域 肿瘤  细胞生物  细胞粘附分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CEACAM21
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) family contain a single N domain, with structural homology to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. CEACAM21 (carcinoembryonic antigen-related cell adhesion molecule 21) is a 293 amino acid single-pass type I membrane protein that belongs to the CEACAM family and contains one Ig-like C2-type domain. CEACAM21 exists as three alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 19.

Subcellular Location:
Membrane; Single-pass type I membrane protein (Potential).

Similarity:
Belongs to the immunoglobulin superfamily. CEA family. 
Contains 1 Ig-like C2-type (immunoglobulin-like) domain. 

Database links:
UniProtKB/Swiss-Prot: Q3KPI0.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.