Anti-ASB8抗体May be a substrate-recognition component of a SCF-like ECS （Elongin-Cullin-SOCS-box protein） E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal

产品编号 yb-9132R
英文名称 Anti-ASB8抗体
中文名称 含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族8抗体
别    名 Ankyrin repeat and SOCS box containing 8; Ankyrin repeat and SOCS box protein 8; ASB 8; ASB-8; ASB8; ASB8_HUMAN; FLJ21255; MGC5540; PP14212.
Anti-ASB8抗体
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  免疫学  细胞周期蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ASB8
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Function:
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). 

Subcellular Location:
Cytoplasm

Tissue Specificity:
Highest level of expression in skeletal muscle. Also expressed in heart, brain, placenta, liver, kidney and pancreas.


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.