Anti-蛋白激酶A2抗体AKAP2 binds to regulatory subunit （RII） of protein kinase A and can be differentially expressed as a natural AKAP2-PALM2 chimeric protein.

产品编号 yb-9028R
英文名称 Anti-蛋白激酶A2抗体
中文名称 蛋白激酶A2抗体
别    名 A kinase (PRKA) anchor protein 2; A kinase anchor protein 2; AKAP 2; AKAP KL; AKAPKL; KIAA0920; PALM 2; PALM2; PRKA 2; PRKA2; Protein kinase A anchoring protein 2; Protein kinase A2; AKAP2_HUMAN.
Anti-蛋白激酶A2抗体 
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  免疫学  信号转导  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Chicken, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 95kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human AKAP2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-蛋白激酶A2抗体
PubMed PubMed
产品介绍 background:
AKAP2 binds to regulatory subunit (RII) of protein kinase A and can be differentially expressed as a natural AKAP2-PALM2 chimeric protein. It may be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP. There are 2 named isoforms produced by alternative splicing.

Function:
Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity). 

Anti-蛋白激酶A2抗体
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.