Anti-ABHD1抗体The alpha/beta hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases.

产品编号 yb-7942R
英文名称 Anti-ABHD1抗体
中文名称 肺α/β水解酶蛋白1抗体
别    名 Abhd1; ABHD1_HUMAN; Abhydrolase domain containing 1; Abhydrolase domain-containing protein 1; Alpha/beta hydrolase domain containing protein 1; FLJ36128; LABH1; Lung alpha/beta hydrolase 1; Lung alpha/beta hydrolase protein 1.
Anti-ABHD1抗体
说 明 书 0.2ml  
研究领域 细胞生物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ABHD1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4
PubMed PubMed
产品介绍 background:
The alpha/beta hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical alpha/beta hydrolase fold, which consists of an eightstranded parallel alpha/beta structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer’s disease, obesity and blood clotting disorders. The Ab hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostly uncharacterized members, most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD1 is a 405 amino acid single-pass type II membrane protein that belongs to the AB hydrolase superfamily and the AB hydrolase 4 family. Ubiquitously expressed, ABHD1 plays a role in metabolizing smoking xenobiotics.

Subcellular Location:
LOCATION] Membrane; Single-pass type II membrane protein (Potential). 

Tissue Specificity:
Ubiquitously expressed. 

Similarity:
Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. 

Database links:

Entrez Gene: 84696 Human

Omim: 612195 Human

SwissProt: Q96SE0 Human

Unigene: 375791 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.