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产品介绍/ PRODUCT PRESENTATION产品编号 yb-2077R
英文名称 Anti-AMPD1抗体
中文名称 腺苷单磷酸脱氨酶1抗体
别 名 AMPD1; AMPD-1; AMPD1; AMPD-1; Adenosine monophosphate deaminase 1 (isoform M); Adenosine monophosphate deaminase 1; AMP deaminase 1; AMP deaminase isoform M; AMPD 1; Ampd01; MAD; MADA; Myoadenylate deaminase; RATAMPD01; AMPD1_MOUSE.
nti-AMPD1抗体
说 明 书 0.2ml
研究领域 细胞生物 信号转导 激酶和磷酸酶
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 86kDa
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse AMP deaminase 1 (125-175aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
nti-AMPD1抗体
PubMed PubMed
产品介绍 background:
AMP deaminase (AMPD) is an allosteric enzyme that plays a critical role in energy metabolism. There are three functional isoforms of AMPD. AMPD1 is the skeletal muscle-specific isoform M located in type II muscle fibers, neuromuscular junctions and in capillaries. Defects in AMPD1 are the cause of adenosine monophosphate deaminase deficiency muscle type (AMPDDM). AMPDDM is a metabolic disorder resulting in exercise-related myopathy. It is characterized by exercise-induced muscle aches, cramps, and early fatigue.
Function:
AMP deaminase plays a critical role in energy metabolism.
Subunit:
Homotetramer
Similarity:
Belongs to the adenosine and AMP deaminases family.
Database links:
UniProtKB/Swiss-Prot: Q3V1D3.1
v
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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