Anti-AIFM3抗体Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.

产品编号 yb-6791R
英文名称 Anti-AIFM3抗体
中文名称 凋亡诱导因子3抗体
别    名 AIFL; Aifm3; AIFM3_HUMAN; Apoptosis inducing factor 3; Apoptosis inducing factor like; Apoptosis inducing factor like protein; Apoptosis inducing factor, mitochondrion associated; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like protein; FLJ30473; FLJ45137.
Anti-AIFM3抗体
说 明 书 0.2ml  
研究领域 细胞生物  细胞凋亡  线粒体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Cow, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 67kDa
细胞定位 细胞浆 线粒体
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human AIFM3 (21-65aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.

Function:
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.

Subcellular Location:
Mitochondrion. Note=Does not translocate to the nucleus upon induction of apoptosis.

Tissue Specificity:
Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).

Similarity:
Belongs to the FAD-dependent oxidoreductase family.
Contains 1 Rieske domain.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.