Anti-ANGPTL6抗体Angptl6 （angiopoietin-like 6） is a 470 amino acid secreted protein that contains one fibrinogen C-terminal domain and is a member of the angiopoietin-like family.

产品编号 yb-7027R
英文名称 Anti-ANGPTL6抗体
中文名称 血管生成素相关蛋白6抗体
别    名 ARP5; AGF; Angiopoietin like 6; Angiopoietin like Protein 6; Angiopoietin related Growth Factor; Angiopoietin related protein 5; Angiopoietin-like protein 6; Angiopoietin-related growth factor; Angiopoietin-related protein 5; Angiopoietin-related protein 6; ANGL6_HUMAN; Angptl6; ARP5.
 Anti-ANGPTL6抗体  
说 明 书 0.1ml  0.2ml  
研究领域 心血管  细胞生物  血管内皮细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Horse, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
细胞定位 分泌型蛋白 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ANGPTL6
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
 
PubMed PubMed
产品介绍 background:
Angptl6 (angiopoietin-like 6) is a 470 amino acid secreted protein that contains one fibrinogen C-terminal domain and is a member of the angiopoietin-like family. Expressed abundantly in liver and present at lower levels in testis, kidney, heart, brain and lung, Angptl6 plays a role in wound healing and is also thought to promote neovascularization and enhance the chemotactic activity of endothelial cells. Additionally, Angptl6 may be involved in epidermal proliferation, remodeling and regeneration and may be able to counteract obesity by increasing energy expenditure. Human Angptl6 shares 74% amino acid identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding Angptl6 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).

Function:
May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure.

Subcellular Location:
Secreted (Probable).

Similarity:
Contains 1 fibrinogen C-terminal domain.
 

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.