Anti-ACSL1抗体又称安非它命，属中枢神经系统兴奋剂类，能够增加人的机敏性，暂时减轻疲劳感并增加攻击性。曾是体育界滥用Z严重的一种兴奋剂。

产品编号 yb-5022R
英文名称 Anti-ACSL1抗体
中文名称 长链脂肪酸*连接酶1/2抗体
别    名 ACS 1; ACS1; ACSL 1; Acyl CoA synthetase 1; Acyl CoA synthetase long chain family member 1; FACL 1; FACL 2; FACL1; FACL2; Fatty acid Coenzyme A ligase long chain 1; Fatty acid Coenzyme A ligase long chain 2; LACS 1; LACS 2; LACS; LACS1; LACS2; Lignoceroyl CoA synthase; Long chain acyl CoA synthetase 1; Long chain acyl CoA synthetase 2; Long chain fatty acid CoA ligase 1; Long chain fatty acid CoA ligase 2; Long chain fatty acid coenzyme A ligase 1; Palmitoyl CoA ligase 1; Palmitoyl CoA ligase 2; ACSL1_HUMAN.
Anti-ACSL1抗体   
说 明 书 0.2ml  
研究领域 肿瘤  细胞生物  免疫学  转录调节因子  结合蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 77kDa
细胞定位 细胞浆 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ACSL1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. [provided by RefSeq, Jul 2008].

Function:
Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate. 

Subcellular Location:
Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein

Tissue Specificity:
Highly expressed in liver, heart, skeletal muscle, kidney and erythroid cells, and to a lesser extent in brain, lung, placenta and pancreas. 

Similarity:
Belongs to the ATP-dependent AMP-binding enzyme family.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.